Archive for the ‘Steroid Profiles’ Category

Test Suspension.

August 19th, 2010 meetsteroids.com

Testosterone Suspension is an injectable hormone in a water base that was developed and used for decades and is actually the first anabolic, androgenic steroid used. For the purpose of building mass, Testosterone Suspension has never been surpassed since it was first developed in the 1930´s. Many underground labs also suspend this product in propylene glycol or oil as well (which makes for a very painful injection). It has no ester attached; therefore no ester is calculated into the weight. This is extremely beneficial to the user since 100mg of testosterone suspension will yield 100mg of testosterone unlike the other esterfied testosterones such as (for example) testosterone enanthate which only yields 72mg of actual testosterone per 100mg of total weight. Testosterone suspension considerably raises the storing of glycogen in the muscle cells and because it is dissolved in water it becomes effective immediately. Also making it different from other esterfied hormones is that it only keeps sustained and elevated testosterone levels for 2-3 days due to its micro-crystal design. This forces the user to inject on a daily basis, with better results coming from twice-three time a day use due to its short active-life with the effective dose ranging from 350-1000mg per week (50-140mg/day). One should practice site rotation and should practice injecting in the same spot only once per week at most. It should be noted that test suspension is usually a very painful shot, so it is often cut with something else, such as B-12, or other steroids. And yes, you can mix a water based steroid with an oil based steroid in the same syringe. It looks like a lava lamp, and you can use it as a level if you are building something, but no, there´s no problems with injecting a mixture like this.

Note that due to the water base (though, not an issue if using a product suspending in propylene glycol or oil) the testosterone will most likely settle to the bottom of the vial and that shaking the vial is needed in order to insure even dosing. This is true for all water based steroid suspensions.

As was noted before, testosterone can be considered one of the most powerful mass builders and testosterone suspension can be considered one of the most powerful of the testosterones simply due to the fact that it has no attached ester. This means that you are getting 100mgs of Test per 100mgs you inject; Suspension is the only version of Testosterone that can boast that claim. A growing reason why many athletes are choosing to use testosterone suspension instead of enanthate or other forms (besides the fact that it has a higher amount of pure testosterone resulting in greater results) is that it may be responsible for localized growth at the site inject like winstrol. Most athletes will also only use this form of testosterone in a bulking cycle as it is usually accompanied by high water retention, severe bloat, adipose storage, and gynomastia. This product also has a high level of aromitization into estrogen and coverts to DHT (dihydrotestosterone) as well. Of course, adding endogenous testosterone to your body will result in the shutting down of your own exogenous testosterone levels, as well as the hormones secreted which cause testosterone to be secreted by your testes.

Testosterone is many times not used by women because male secondary sex characteristics may start to appear in female users. However, testosterone suspension will allow women to site-inject and help problem areas common in women such as calves and inner thighs, and can be used in small enough doses, clearing the system quickly if sides develop, that some women use choose to use it. This advantage also means that one can pass a drug test a couple of days after the last injection. This is a great advantage to athletes who will be tested and still want the benefits of a mass drug which can not be tested for easily….many other forms of testosterone (such as Cyp or Enanth) can take 3 months to become undetectable.

As far as results of the cycle, one should be very happy with the results as so far as the diet and training regimen are good. As I previously stated, testosterone is a highly anabolic and androgenic hormone, it has an anabolic (muscle building) rating of 100, making it a good drug to use if one is in pursuit of more size and strength. And if you aren´t in pursuit of more size and strength, then why would you be reading this, right? Well, let´s get on with it and look at exactly what makes testosterone a good mass builder. Firstly, testosterone promotes nitrogen retention in the muscle(2) the more nitrogen the muscles holds the more protein the muscle stores. Testosterone can also increase the levels of another anabolic hormone, IGF-1, in muscle tissue(3). Testosterone also has the amazing ability to increase the activity of satellite cells(4). These cells play a very active role in repairing damaged muscle. Testosterone also binds to the androgen receptor to promote A.R dependant mechanisms for both muscle gain as well as fat loss.(5) Testosterone significantly increases the concentrations of the A. R in cells which are critical for muscle repair and growth.(4, 6 ). Testosterone induces changes in shape and size of your muscle fibres, and also can change the actual appearance and the number of muscle fibres(7). Also of note to both bodybuilders and athletes is that many anabolic/androgenic steroids (like testosterone susprnsion, in this case) can also protect your hard earned muscle from the catabolic (muscle wasting) glucocorticoid hormones(8) that your body employs to maintain homeostasis. In addition, Testosterone has the added ability to increase red blood cell production(9), and a higher RBC count may improve endurance via better oxygenated blood. More RBCs can also improve recovery from strenuous physical activity, and this has obvious benefits for the hard training bodybuilder or athlete. As with 99% of other steroids, Testosterones´ anabolic/androgenic effects are dose dependant, the higher the dose the higher the muscle building effect(10).

Testosterone suspension is best run for at least 8 weeks and depending on the experience of the user one may choose to runs for much longer. Since this hormone is primarily used by more advanced users other drugs are usually incorporated into the cycle. One should opt for other mass drugs such as dianabol and deca-durabolin since the goal of this cycle will most likely be and should be for mass. The user should expect to see rapid muscle growth, water retention, and possibly extra fat deposits. Some athletes will also choose to inject Suspension before a workout or competition (this would increase aggression, and would be especially important for MMA competitors, or those in a sport where aggression is a benefit). I´ve used it for this purpose and found it to be very useful. Many pther athletes will also use it solely for this purpose….every day (painful) shots are just not much fun for a typical 12 week cycle. It is for this reason that most people who use this drug employ it pre-workout and/or competition, and not much more often. A mere 100mgs pre-workout or competition is sufficient, and would benefit competitive athletes greatly enough to justify it´s inclusion during an in-season-cycle.

Lastly, you should be paying roughly $50 for a 10cc bottle of 100mgs/ml from any reputable Underground Lab.

Read More »
Posted in Steroid Profiles Tags: , , , , , , , , , , , , , , No Comments »

Nandrodex 300

August 11th, 2010 meetsteroids.com

Manufacturer: Sciroxx
Substance: Nandrolone Decanoate
Pack: 10 ml vial (300 mg/ml)

Average Dose: 300-800 mg/week(M) 50-100 mg/week(F)
Half Life: Two Weeks
Water Retention: Yes, some
Aromatization: Low
DHT Conversion: No

Deca Durabolin (Nandrolone Decanoate) is actually the brand name for Organon´s version of the compound Nandrolone Decanoate. This is a 19-Nor compound (some would say that it is the 19-nor compound), and as such, it shares basically the same characteristics with all of them. One thing unique to Deca, above nearly all steroids, is the mystique it has had for the last quarter of a century. On a personal level, I´ve included Deca in cycles at doses ranging from 100mgs/week to 2,000mgs per week. Suffice to say, I have my fair share of experience with this compound. This drug was regarded very highly by Dan Duchaine in his Underground Steroid Handbooks as well as many of his later writings. For many, this was and is the final word on Deca. Let´s delve into some of the reasons that Deca´s mystique may be well deserved.

First of all, Deca (and Nandrolone in general) doesn´t produce many estrogenic or androgenic side effects. This is because Deca has a very low rate of aromatization (conversion to estrogen via the aromatase enzyme), roughly equal to 20% the rate of Testosterone.

Also, I´ve read many places that Deca stores water in connective tissue, thus alleviating joint pain. I have no idea what “storing water in the joints” means. I have no idea how to really quantify that statement, or where it started. However, in one study of postmenapusal women, Deca impoved collagen synthesis (1), and in another study deca increased bone mineral content. (2)Both of these studies used VERY low doses, which were far too low to promote muscle growth. In my estimation, based on these 2 studies, an athlete attempting to use Deca only for these two effects (increasing bone mineral content and collagen synthesis) should be using 100mgs of deca every week. That´s actually a higher dose than those two studies used successfully. Even at ½ of this dose, in HIV+ patients who have experienced significant wasting, a 100mg/E2W (every 2 weeks) injection of Deca resulted in a “significant increase in weight” (5). I´d never recommend that low of a dose for an athlete, but it´s evidence of Deca´s strong anabolic properties. Deca is a very nice anabolic, causing nice (albeit slow) gains in quality muscle. This could be due to its moderately strong binding to the Androgen Receptor, or its many positive non-Androgen-Receptor mediated effects. One such effect is nitrogen retention, which is a major factor in muscle growth and lean mass gains; in one study, with low-doses (65 mg/week) and high-doses of Deca (200 mg/week), both low-doses and high-doses resulted in significant nitrogen retention (33-52 g nitrogen/14 days, representing gains of 0.5 to 0.9 kg lean tissue/week), and body weight increased by 4.9 +/- 1.2 kg, including 3.1 +/- 0.5 kg lean body mass, and treadmill exercise performance (cardiovascular fitness) also improved (7). Need I say that the higher doses in this study produced more gains? Steroid.com members who have posted their results with deca confirm this in many posts and threads, with their average reccomendation being to take 400-600mgs/week for muscle gain. I have to agree.

Deca also has a very long active life. We can see from the chart below that a 100mg shot Deca (represented by the circles) produced relatively active and stable plasma nandrolone levels until day almost 10, hence once a week shots are all that´s necessary for stable levels of nandrolond decanoate (as a side note, the nandrolone phenylpropionate used in this study was active, and only experienced a severe drop off around day 5, shooting NPP every 4th day is the way to go). You´ll also note that higher blood plasma levels of Nandrolone are found with Gluteal injections as opposed to Deltoid injections (this is true for all oil-based steroids, I suspect).

In another study of HIV+ men (6) we can see that deca ( 200mgs on week 1, 400 on week 2 and 600mgs for weeks 3-12) caused NO negative side effects in total or LDL cholesterol, triglycerides, or insulin sensitivity and there was a reduction of HDL cholesterol(8-10 points) in both groups. Also, in most studies with HIV+ subjects, deca also improved immune function.

So what do we know so far about this compound? So far, we know that Deca is a very safe drug for long term use, will help with joint problems, could improve immune function, and is highly (!) anabolic, and not very androgenic.

That´s the good news (and there´s a lot of it), now for the bad news:

Deca is known for producing quality weight gains, but it has to be used for 12 weeks at a minimum, judging from Steroid.com members´ feedback, as well as my own personal experience. This shouldn´t cause any problems, since it is a very mild drug in terms of side-effects.

Deca Durabolin Side Effects

Many members of Steroid.com also complain of water-retention with this drug, and again, I´m inclined to agree. Letrozole seems to be a preferred choice to combat this, and it´s my favorite for this use. This water retention would seem to make Deca more suitable for bulking rather than cutting, although it can be successfully used for either.

Now for the worst news: Deca is a progestin (as are all nandrolones), unfortunately; it happens to stimulate the progesterone receptor 20% as well as progesterone itself (3), and this opens the door for many possible unwanted side effects (water retention, acne, etc…). It must be noted that most of those are rare, though. This also may be the major reason that Deca is such a suppressive drug when it comes to your natural testosterone levels. We can see from the chart below that a simgle measly 100mg injection of Deca caused a total (100%) reduction of natural testosterone levels, and it took roughly a month to return those testosterone levels to baseline! All from 100mgs of Deca!

The moral of this story? Always use Testosterone with your Deca! I suggest 200mgs, minimum, to avoid impotence and sexual dysfunction. For an anabolic effect from that Testosterone, I recommend at least double that, with an equal amount of deca (minimum). I´d also recommend taking an anti-progesteronic drug with deca (or at least having it on hand): Cabergoline and Bromocriptine are both good choices.

Deca Durabolin Cycle

So where are we? Well, I´d be comfortable recommending Deca for use in a bulking cycle at up to 600mgs/week for an extended duration (12-16 weeks), or up to 400mgs/week in a cutting cycle (again, for 12-16 weeks), as long as something to combat water retention is present. Whichever purpose you decide to use Deca for, you still need to include Testosterone in your cycle and have some anti-progesteronic drugs on hand (see paragraph above), just in case.

Post Cycle Therapy (PCT), though beyond the scope of this profile, needs to be commented on. Due to the highly suppressive nature of Deca, I will speculate that testosterone in a deca-inclusive cycle needs to be run for at least 2 additional weeks upon cessation of Deca. We remember from the chart above that baseline testosterone levels took roughly a month to return. Hence, a nice long estered testosterone should be run about 2 weeks longer than deca, to prevent having a lag in time when the deca is not producing an anabolic effect, yet is still suppressing your natural testosterone levels. I´d also suggest that a particularly aggressive PCT be run after your cycle; nolvadex, HCG, and perhaps clomid should all be utilized in an effort to restore your natural hormone levels as quickly and efficiently as possible.

Read More »
Posted in Steroid Profiles Tags: , , , , , , , , , , , No Comments »

Primobolan Injectable.

July 22nd, 2010 meetsteroids.com

Primobolan is an anabolic steroid which became very popular once it was claimed that it was one of Arnold’s favorites. I’m not really sure why this is, or how likely it is that Arnold went around telling everyone’s favorite steroid- but nonetheless, this rumor has persisted through the years.

When we take a critical look at it, in terms of its anabolic and androgenic rating, it appears to be a pretty weak steroid but is rated as stronger than Masteron (Drostanolone)! I’ve used both steroids and can tell you that not too many people would claim that those ratings provide an accurate idea of those two steroids compare to each other. In truth, I used Primobolan at 400mgs/week and wasn’t very impressed with it, and honestly, for the money, that’s really disappointing, since Primobolan is not inexpensive. I also would speculate that the reason many (male) Primobolan users have been less than thrilled with results from it is that they failed to use high enough doses. If I were to use it again (which I won’t), I would probably use 100mgs/ED (Every Day).

Interestingly, Primobolan has a relatively high affinity for binding to the Androgen Receptor, and surprisingly it actually binds with more affinity than testosterone (1). This ability to strongly bind to the AR may be why Primobolan is considered a good fat burner- although most Dihydrotestosterone (DHT) derivations are very potent fat burners (the notable exception being Anadrol).

Primobolan has been used medically to reduce breast tumors, with a success rate of about a third (2), so we can safely assume that no Anti-Estrogen products would be necessary. The use of Finasteride, Dutesteride, or another anti-hair-loss product may be useful, however, as Primobolan has a bad reputation for causing Alopecia.

Primobolan is very useful as both an anabolic as well as anti-catabolic agent, and the probable cause for this property is its ability to aid in nitrogen retention (3), which is a useful trait on both a bulking or cutting cycle…once again, I have to reiterate that the expense of this drug probably makes it a poor choice on a bulking cycle because of the reasonably high doses that it would require.

One of the other very interesting facts about Primobolan is that it’s one of the very few compounds available as both an oral as well as an injectable. Unlike Winstrol and Dianabol (both alkylated and non-estrified steroids) however, which are also available in both forms, Primobolan is available with an Acetate ester for use as an oral, and with an Enanthate ester as an injectable. Unfortunately, in this case, making Primobolan a non-17-alpha-alkylated steroid greatly reduces its potency. However, it must be noted that this alkylation is what makes oral steroids survive their first pass through the liver; it also makes them hepatoxic (liver –toxic). Oral Primobolan doesn’t actually have this drawback, and thus it is very mild on liver function and doesn’t elevate liver enzymes too much. Instead of the more toxic 17a-alkylation, Primobolan (Oral) uses 17 beta estrification and 1 alkylation to make it orally available. For both men as well as women, daily dosing of the oral is necessary, although men would probably want to take 100mgs per day and women would need to take at least 10mgs every day.

Although it is typically considered to be a very mild drug when inhibition of the natural hormonal profile is considered, this isn’t totally true. Men were given a 30-45mg dose of the oral version of Primobolan, experienced between a 15% and 65% decrease in their Gonadatropin levels (4). Since we’re probably looking at double or triple that dose, for men to get any kind of results, it’s also probable that gonadal inhibition will also be increased.

My history with Primobolan Enanthate (the injectable version) has been less than impressive. I used it at 200mgs/week about a decade ago, and wasn’t impressed at all. A couple of years ago I went back to it and used 350mgs/week (100mgs/Every other Day), and got much better results, but still wasn’t overly impressed with it. Add to that the fact that it is an expensive chemical, and I really wasn’t impressed.

On the Black Market, Primobolan tabs are only being produced by British Dragon currently, although PaperPrimo is being produced as well. Both are high quality products, although I would speculate that their use is going to be reserved for women. With regards to the injectable version, many underground labs produce it, and quality tends to vary, due to powder quality at the moment. Expect to pay around $100 for a 10ml bottle dosed at 100mgs/ml, if not more. Finally, ampules are available at a cost of roughly $7-12 per amp, but since this is the most widely counterfeited steroid on the black market, I’d stick to the underground lab variety.

Read More »
Posted in Steroid Profiles Tags: , , , , , , , , , , , , , , No Comments »

Anavar.

July 19th, 2010 meetsteroids.com

Partly this is due to its apparent lack of non-AR-mediated activity. This can be corrected of course by stacking with a Class II steroid such as Dianabol, Anadrol®, 4-AD, or nor-4-AD: the latter two steroids require high blood levels which are not obtained by oral use of the powders.

The other part of the reason for this is that bodybuilders make unfortunate and unreasonable comparisons when judging anabolic steroids. If say 8 tablets per day does little, then the drug is pronounced useless or weak by the user. But that is only 20 mg/day, or 140 mg/week. Does 140 mg/week testosterone give much results?  No. Few anabolic steroids give dramatic results at that dose. Per milligram the potency is reasonable, but each individual tablet is weak because the dosage is small.

Because of its high price, very few bodybuilders have taken large doses of oxandrolone. There is a single case in the medical literature (Forbes et al.) where it is reported that a competitive athlete self-administered 150 mg oxandrolone per day with remarkable gains. This is of uncertain credibility because unless urinalysis was done to verify that no other steroids were taken, there is no way to be certain that the athlete did not actually take more drugs than he reported. In any case, at current prices, only the quite wealthy could afford such a dose. I personally have tried 150 mg/day and considered it somewhat effective, but not dramatically so, and not a preferred regimen.

Oxandrolone does not aromatize or convert to DHT, and has a longer half life than Dianabol – 8 hours vs. 4 hours. Thus, a moderate dose taken in the morning is largely out of the system by night, yet supplies reasonable levels of androgen during the day and early evening.

Oxandrolone shares the liver toxicity problems common to 17-alkylated steroids. At one time it was thought that it did not, but both clinical and practical experience with Oxandrin has shown that at doses of  40 mg/day and higher, liver toxicity is indeed an issue with prolonged use.

Primobolan, I believe, should be considered a superior compound, offering the same activity at (usually) a lower price and without the alkylated-toxicity issue.

Oxandrolone is the chemical name of active ingredient in Oxandrin and Anavar. Oxandrin is a registered trademark of Bio-Technology General Corp. in the United States and/or other countries. Anavar was originally the registered trademark of Searle Laboratories.

Read More »
Posted in Steroid Profiles Tags: , , , , , , , 1 Comment »

Tamoxifen Nolvadex

July 9th, 2010 meetsteroids.com

Nolvadex is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure.

It is not correct that Nolvadex reduces levels of estrogen: rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.

The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Nolvadex. The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction in IGF-1 (individuals using anabolic steroids were not studied though) from use of Nolvadex. Thus, Dan Duchaine reported that it reduces IGF-1 and therefore reduces gains. However, if this effect exists at all, it must be very minor, due to the excellent gains that many have made, and from the fact that no one has noticed any such thing from Clomid, which has the same activity profile.

However, I would not be surprised if one were to tell a steroid user that Clomid reduced his gains, he would immediately become afraid that Clomid reduced his gains (please note that no one I have ever heard of has noticed this.) Not having been so misled, however, he would not conclude this from his results. But if an authority publishes that such an effect occurs, whether it does or not it can become self-fulfilling by biasing the user.

The fact that Nolvadex will reduce water retention may result in the user agreeing that gains are less, since weight gain is less, thus reinforcing the bias.

Tamoxifen citrate is the chemical name of active ingredient in Nolvadex. Nolvadex is a registered trademark of AstraZeneca UK Limited in the United States and/or other countries.

Read More »
Posted in Steroid Profiles Tags: , , , , , , , , , , No Comments »

Deca Durabolin

July 6th, 2010 meetsteroids.com

This drug is unique (so far as I know) in that 5a -reductase, the enzyme which converts testosterone to the more-potent DHT, actually converts nandrolone to a less-potent compound. Therefore this AAS is somewhat deactivated in the skin, scalp, and prostate, and these tissues experience an effectively-lower androgen level than the rest of the body. Therefore, for the same amount of activity as another drug at the androgen receptors (ARs) in muscle tissue, Deca gives less activity in the scalp, skin, and prostate. Thus, it is the best choice for those particularly concerned with these things.

Its effectiveness at the androgen receptor of muscle tissue is superior to that of testosterone: it binds better. Yet, it gives only about half the muscle-building results per milligram. This I think is a result of its being less effective or entirely ineffective in non-AR-mediated mechanisms for muscle growth.

It also appears less effective or entirely ineffective in activity on nerve cells, certainly on the nerve cells responsible for erectile function. Use of Deca as the sole AAS often results in complete inability to perform sexually.

These problems can be solved by combining with a drug that does supply the missing activity: e.g. testosterone.

Nandrolone is proven to be a progestin. This fact is of clear importance in bodybuilding, because while moderate Deca-only use actually lowers estrogen levels as a consequence of reducing natural testosterone levels and thus allowing the aromatase enzyme less substrate to work with, Deca nonetheless can cause gyno in some individuals. Furthermore, just as progesterone will to a point increase sex drive in women, and then often decrease it as levels get too high, high levels of progestogenic steroids can kill sex drive in male bodybuilders, though there is a great deal of individual variability as to what is too much.

Incidentally, this progestogenic activity also inhibits LH production, and contrary to common belief, even small amounts of Deca are quite inhibitory, approximately as much so as the same amount of testosterone.

To some extent, nandrolone aromatizes to estrogen, and it does not appear that this can be entirely blocked by use of aromatase inhibitors –  indeed, aromatase may not be involved at all in this process (there is no evidence in humans that such occurs) with the enzyme CYP 2C11 being in my opinion the more likely candidate for this activity. In any case, Cytadren, an aromatase inhibitor, has not been found effective in avoiding aromatization of nandrolone.

The drug is moderately effective at doses of 400 mg/week. The long half-life of nandrolone decanoate makes it unsuited to short alternating cycles, but suitable for more traditional cycles, with a built-in self-tapering effect in the weeks following the last injection.

Nandrolone decanoate is the chemical name of active ingredient in Deca Durabolin. Deca Durabolin is a registered trademark of Organon Corporation in the United States and/or other countries.

Read More »
Posted in Steroid Profiles No Comments »

Clomid

June 30th, 2010 meetsteroids.com

Clomid is not an anabolic/androgenic steroid. Since it is a synthetic estrogen it belongs, however, to the group of sex hormones. In school medicine Clomid is normally used to trigger ovulation. Clomid also has a strong influence on the hypothalamohypophysial testicular axis. It stimulates the hypophysis to release more gonadotropin so that a faster and higher release of FSH (follicle stimulating hormone) and LH (luteinizing hormone) occurs. This results in an elevated endogenous (body’s own) testosterone level. Clomid is especially effective when the body’s own testosterone production, due to the intake of anabolic/androgenic steroids, is suppressed. In most cases Clomid can normalize the testosterone level and the spermatogenesis (sperm development) within 10- 14 days. For this reason Clomid is primarily taken after steroids are discontinued. At this time it is extremely important to bring the testosterone production to a normal level as quickly as possible so that the loss of strength and muscle mass is minimized. Even better results can be achieved if Clomid is combined with HCG or when Clomid is used after the intake of HCG.

Paradoxically, although Clomid is a synthetic estrogen it also works as an anti-estrogen. The reason is that Clomid has only a very low estrogenic effect and thus the stronger estrogens which, for example, form during the aromatization of steroids, are blocked at the receptors. These would include those that develop during the aromatizing of steroids. This does not prevent the steroids from aromatizing but the increased estrogen is mostly deactivated since it cannot at-tach to the receptors. The increased water retention and the possible signs of feminization can thus be reduced or even completely avoided. Since the antiestrogenic effect of Clomid is lower than those found in Proviron, Nolvadex, and Teslac it is mainly taken as a testosterone stimulant. Clomid is a medication that promotes the production of the body’s own stimulating hormone, gonadotropin, which in turn increases the testosterone level. It is, for example, administered to women as a so-called anti-estrogen to trigger ovulation (“ovulation stimulator”).

Side effects of Clomid are very rare if reasonable dosages are taken. Possible side effects are climacteric hot flashes and occasional visual disturbances, which can manifest themselves in blurred vision, giving flickering or flashing. Should visual disturbances occur, the manufacturer recommends discontinuing Clomid treatment. Inadequate liver functions cannot be excluded; however, they are very unlikely. In women enlargement of the ovaries and abdominal pain can occur since Clomid stimulates the ovaries. When taking Clomid multiple pregnancies are possible as well. As for the dosage, 50-100 mg/day (1 -2 tablets) seems to be sufficient. The tablets are usually taken with fluids after meals. If several tablets are taken it is recommended that they be administered in equal doses distributed throughout the day. The duration of intake has been rumored to not be taken for longer than 10-14 days. This is incorrect. Clinical studies with male patients have shown clomid to be used for up to a year or longer. Most athletes begin with 100 mg/day, taking one 50 mg tablet every morning and evening after meals. After the fifth day the dosage is often reduced to only one 50 mg tablet per day. It is normally not necessary to take the compound for more than ten days in order to increase the endogenous testosterone production. Clomid is relatively expensive. A package with 10 tablets costs approx. $35 – 45 on the black market.

Read More »
Posted in Steroid Profiles Tags: , , , , No Comments »

Anadrol 50. (Oxymetholone)

June 29th, 2010 meetsteroids.com

Anadrol 50

(oxymetholone)

Anadrol 50(commonly called by athletes “A50″ or “A-bombs”) was initially developed as a compound to help people with anemia, and has since been used very successfully to aid people who are suffering from many other diseases where weight loss is a concern. Thus, it is clearly an effective agent for promoting weight gain, increasing appetite, gaining strength, and increasing Red Blood Cell count. And, as with most Anabolic/Androgenic Steroids (AAS), it has it´s downsides as well. Anadrol will inhibit your body´s natural production of hormones (testosterone, etc& ), will negatively affect your blood lipid profile, can cause water retention, is notorious for causing headaches, and is also highly liver toxic (in fact, it has the worst reputation for hepatoxicity out of all steroids). Paradoxically, although one the benefits touted by it´s original manufacturer (Syntex) is that it can be used to stimulate weight gain through increasing appetite, taking too much may actually inhibit your appetite!

Anadrol Effects on Body

I think, in order to gain a complete understanding of the Anadrol effects on body, we need to take a look at its advantages contrasted with its disadvantages. Anadrol is a DHT-derived compound, and is 17-Alpha-Alkylated steroid, meaning that it has been altered at the 17th carbon position to survive oral ingestion. Most oral steroids are 17aa, and this helps them make it through your liver in a useful form. Sounds great, right? Lets 17alpha-alkylate everything! Well& as you can imagine, there´s a down side.

Anadrol Side Effects

This 17aa alteration, which makes it possible for Anadrol to survive its first pass through your liver, also makes it very taxing on your liver. How taxing is A50 and how much weight can you gain from its use? Well, there was a 30 week study done on A50 and, as you can expect, a reasonable amount of side effects were noted. The fact that A50 causes some side effects has really never been in debate. But how effective was the drug? Well, first it should be mentioned that this study was done on people with AIDS related wasting, and they actually gained weight (8+kg) while the control group lost weight, and had increased mortality rates. (1). I suppose, if you´re in a study because you have a wasting disease which is also a terminal illness, you don´t want to end up in the control group& .Anyway, weight gain in this study peaked at 19-20 weeks, though, so the last 10 weeks weren´t very productive in this respect. Clearly, you wouldn´t want to run Anadrol for 20 weeks, given its toxicity, but after that, any effect in terms of weight and strength gains would be negligible. So, with regards to sides from Anadrol, and the sheer fact that this study lasted so long (30 weeks), it should be apparent that they can be kept under control and the drug can be used safely. People are commonly told to limit their intake of A50 to 4 weeks or less& I´m a bit less conservative and think you can easily run A50 for 6 weeks or more.

From personal experience, however, I can tell you that gains from Anadrol are quite dramatic for the first 3 weeks, and then quickly level off. Unfortunately, I find that the side effects experienced from Anadrol (which include a headache, bloating, elevated blood pressure, and a general “unwell” feeling for me) remain for the entire duration of use& .but I find, as usual, side effects for this drug are pretty much half legend and half truth. Since Anadrol is derived from DHT, it can´t actually convert to estrogen (via the aromatase enzyme), and it´s not a progestin or a compound with progestenic activity& so the estrogenic (?) side effects produced by it are of a very mysterious nature. It has been speculated that perhaps it can stimulate the estrogen receptor without actually being converted to estrogen& that´s about as plausible an explanation as I´ve heard& However, things really get strange, when Oxymetholone has been used in studies to alter the female reproductive/menstrual cycle; in those cases, it has lowered plasma progesterone levels! (7)One would expect that an AI (aromatase inhibitor) wouldn´t be of much use with this drug, but many have found that Letrozole (which has, in some cases been shown to reduce estrogen in the body to an undetectable amount)(6) can greatly reduce or even eliminate many of the more noticeable side effects of Anadrol, such as the bloating.

As I´ve stated, however, the sides from this drug are certainly no joke, but are easily preventable, and controllable. One study even showed very few sides for subjects using up to 100mgs of Oxymetholone (2). In the original UnderGround Steroid HandBook, Dan Duchaine states that he used it at doses up to 150mgs/day. Clearly, Anadrol´s hepatoxicity has been a bit exaggerated, in some circles. Be that as it may, my suggestion is still to limit Anadrol´s use to 6 weeks, at a maximum& even if just to err on the side of caution. Of course, I have personally run this drug for much longer..

How should we use Anadrol? I´d probably be willing to include Anadrol in a cycle including injectable steroids, but not other 17aa compounds. I´d make any 6-week-run of this compound begin at the start of a cycle, as a form of “jumpstart” towards seeing gains quickly. The quick gains you will get from Anadrol (up to a pound per day for the first 2 weeks are not uncommon in Steroid.com members) are also just as quick to disappear upon cessation of use& .unless you are simply using it as a kickstarter, while waiting for your other compounds to kick-in. I´ll go out on a limb here and say that utilizing Anadrol as a “Jumpstart” is the most popular use of this drug for athletes and bodybuilders today. I´ll also say that this drug is immensely popular with strength athletes who don´t have to worry about weight classes (Field athletes and strongmen), and with powerlifters in the heavier weight brackets. It´s also important to note that in one study by Schroder et. Al (2) anadrol showed that it has the ability to lower serum SHBG (Sex Hormone Binding Globulin& which binds to your free test and makes it no longer useful for anabolism, among other things) concentrations by 54.9 ± 25.8 and 45 ± 16.2 nmol/l in the 50- and 100-mg treatment groups. This means there will be more free test circulating around your body when you take this drug& clearly, this would produce some synergy when stacked with other steroids. Given the large amounts of weight and strength which can be gained in a relatively short time span on this drug, I´m sure this comes as no surprise to many.

Another important and often understated characteristic of this compound is that Oxymetholone doesn´t bind well to the androgen receptor (Relative Binding Affinity = too low to be determined) (3) which is the lowest I´ve ever read about. Basically, what this tells me is that there are a lot of non-receptor mediated effects from this steroid, making it a very potent addition to ANY BULKING stack, because it won´t be competing for the receptor sites with the other steroids you´re using. It´s also, as you may have guessed a very poor choice for a cutting stack.

ANADROL CYCLES

What is an Anadrol Cycle? How much should you use? Well, this is actually one of the most interesting facts about Anadrol. You see, most steroids produce what we call a “dose respondent curve” which is a fancy way of saying “the more you use, the more you gain.”

Anadrol is one of the few steroids where the dose respondent curve flattens out very quickly. When you take 50mgs of Anadrol, you´ll make some very good gains. When you take 100mgs of Anadrol, you´ll make even more gains. However, it has been found that 100mgs/day is as effective for weight gain as 150mgs/day but produces less side effects and was less toxic (4). I feel that the jump from 50mgs to 100mgs constitutes an acceptable rise in benefit vs. cost, but this is not the case as dosages get over 100mgs. Now, lets see how 50mgs and 100mgs of Oxymetholone actually effect strength, when compared with each other:

Relative (%) changes in strength are shown for the groups receiving placebo (filled bars), 50 mg/day oxymetholone (open bars), and 100 mg/day oxymetholone (gray bars). Nos. above bars represent relative change (%) from baseline to week 12 for the 1-repetition maximum tests of strength. Error bars represent ± 1 SE from the mean. * Significant difference from placebo, P < 0.05; significant difference from placebo by Wilcoxon test, P < 0.02. See text for additional statistical analyses.

As you can see, in this study, doubling the dose of Anadrol nearly doubled the strength gains of the test subjects. Now, when we look at changes in body composition from Oxymetholone (chart below) we can see that although the guys taking the 100mgs (vs. the 50mgs group) had more fat lost and more Lean Body Mass gained, it wasn´t as dramatic as the differences in strength gains between the two groups:

Changes in body composition are shown for the groups receiving placebo (filled bars), 50 mg of oxymetholone per day (open bars), and 100 mg per day (gray bars). Numbers above the bars represent the mean absolute changes and the error bars are ± 1 SE. For total lean body mass (LBM) and total fat, differences among the 3 groups were significant (P < 0.0001, one-way ANOVA). * Significant differences from placebo, P 0.001.

Although I am usually not inclined to posit speculations on why a particular drug does or doesn´t do something, in this case I will. I´m guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body´s natural hormonal system, on par with most other oral steroids, but not as bad as most injectables, and it´s certainly not as harsh on your lipid profile as many anabolics are

Read More »
Posted in Steroid Profiles Tags: , , , , , , No Comments »

Oral Turanabol.

June 27th, 2010 meetsteroids.com

Background

Turinabol was developed in the 1960’s when East German’s were looking for an edge for their Olympic and competitive athletes.  It is currently only obtainable through underground labs.

Steroid Action

This is a slower acting steroid.  When using Turinabol, weight, strength and muscle mass increases will not be overly dramatic; however, they will be of good quality. Turinabol also does not typically create risk for estrogenic side effects, so there is limited water retention or risk for gynecomastia. The user can obtain a hard look to their muscles due to limited water retention.

It is 17-alpha alkylated which means it can be toxic to the liver. Turinabol can also lower the clotting ability of blood. 

Negative side effects are rare but can occur from cycles that are too long or high in dosage.  Shutting off of one’s own natural testosterone production and testicular tumors (extremely rare) are both side effects of such extreme cycles.

Technical Data

In studies done on male athletes that were given 10 mg OT/day over six weeks, no negative health effects or side effects were reported. It was also used in low doses to reduce the binding of SHBG to other steroids.(1)  Oral Turinabol was found to have the ability to reduce SHBG and allow testosterone to be more readily used.

There was one case reported where a male experienced negative side effects from 5 years of using Oral Turinabol at a high dosage (2)(3). It was found to be effective at extremely high dosages by those looking to gain strength and mass, yet athletes looking to obtain gains more quickly and more proficiently in their game were very successful with lower doses of Oral Turinabol.  Olympic level male Shot-putters were able to add 2.5-4m to their shot throws, 10-12m on their Discus throw, and 6-10m to their Hammer throws with in four years of training. Female athletes gained even more.  One female athlete improved her throw from under 18m to over 20m (4).

Women experienced increased and more severe and sometimes intolerable side effects than male users.  Although, sometimes the women were taking doses that surpassed the men’s by almost double (5).

User Notes

Recently, Oral-Turinabol has found its way back into the hands of athletes all over the world. It’s the “new” sexy drug that’s actually very old. It was the East German secret weapon when their sports doping program was at it’s height.

O-T, or T-bol as it’s sometimes called, is a very nice strength and mass drug, and since it can’t convert to estrogen, can even be used on a cutting diet. For this reason, it gets my “most versatile oral” award.

Most users do fairly well with doses between 40 and 60 milligrams per day, taken in divided doses.

Read More »
Posted in Steroid Profiles Tags: , , , , , , , , 8 Comments »

Oral Tren

June 25th, 2010 meetsteroids.com

Methyltrienolone (MT) is a very potent, reasonably toxic, non-aromatizing steroid. Ok. Let´s go over those three points again. First of all, MT is potent. It binds so strongly to the AR (androgen receptor) that it is often used in studies on other androgens to measure how strongly they bind. In other words, this stuff binds onto the AR receptor so strongly that it is pretty much the benchmark for that quality. If you´ve read my profile on Trenbolone Acetate (TA), you´ll note that I said TA is the most potent injectable weapon in our arsenal with regards to ability to bind to the Androgen receptor. That´s still true, because this particular compound is not in our arsenal, and it´s not injectable… it´s simply the oral version of TA (i.e. it is Trenbolone which has undergone modification to become orally active, via the addition of a 17-alph-methyl group). So why is it important that this stuff binds so tightly to the AR? Well, Androgen Receptors are found in both fat cells as well as muscle cells; they act on the AR in muscle cells to promote growth, and in the fat cells to affect fat burning. The stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose (fat)tissue. Unfortunately, that strong binding doesn´t also automatically mean that it will elicit the strongest possible anabolic response, nor that the weakest bind will elicit a weak anabolic response. Anadrol (oxymetholone) has the weakest bind to the AR possible (too low to be measured), and it produces a profound anabolic response, for example. Dianabol is simarly low, and produces a very good anabolic response. AR´s are found in both muscle tissue as well as adipose tissue. When a muscle´s AR is stimulated, it can induce hypertrophy. When an adipose tissue´s AR is stimulated, through various related mechanisms, fat is lost. This is a gross oversimplification. Whatever. All we need to know is that when you have a steroid that binds to the AR, it builds muscle and burns fat. And a steroid that binds very tightly to the AR will stimulate a lot of muscle synthesis and burn a lot of fat. A good example of this is Trenbolone. And since I mentioned Trenbolone, its worth further mentioning that MT is basically a 17aa (oral) version of (injectable) Trenbolone. AR binding and AR stimulation is not the only mechanism which stimulates anabolism, however. It is important to note that dbol has a very low AR binding ability and A50 has an AR binding ability which is too low to even measure! Both are very potent oral steroids, though. So while it´s important, AR binding/stimulation is not the end all & be all of anabolism, although it is an important part. Don´t be fooled by the anabolic/androgenic ratio of this (or any steroid), either. The anabolic/androgenic ratio of MT would suggest that it produces 120(+)x the anabolic and 60(+)x androgenic effect of Test-osterone (which has a score of 100 and 100 respectively). If one were able to get a bottle of this stuff, I believe it would be best used as part of a cutting cycle, stacked with some injectables (testo-steron, etc… ), but certainly no other orals. It´s just too toxic. Negma (the French company who brought Parabolan to the market, and then discontinued it) never pushed MT to gain approval as a commercially released item, since their original studies showed it to be highly toxic. Methyltrienolone is, of course, a 19Nor compound (as is Trenbolone)…Thus, it will effect your sexual drive and performance in a similar way to both Tren and Nandrolone, meaning that Temporary Impotence and/or a lack of libido is highly possible.(10). Another problem with MT is that it is a progestin, and binds shockingly well to the progesterone receptor also (PgR) . As we know, progestins amplify estrogenic effects of Aromatizing drugs. Although MT doesn´t aromatize, you will still need to worry about its ability to cause side-effects by amplifying the estrogenic issues caused by the other compounds you may be taking. How toxic is this stuff? Well, it was never commercially marketed for use in humans, and has been relegated to Steroid-Purgatory, to be used only in studies. I´d probably rate it on around the same level as taking very high doses of halotestin or methyltestosteron.

Read More »
Posted in Steroid Profiles Tags: , , , , , , 4 Comments »
« Older Entries
Twitter Delicious Facebook Digg Stumbleupon Favorites More

  • Search

  • Featured Video

Free Sprint Phones with Plans | Thanks to CD Rates, Conveyancing and Registry Software
| Bodybuilding steroids | Bodybuilding Training | steroid cycles |