Methyltrienolone (MT) is a very potent, reasonably toxic, non-aromatizing steroid. Ok. Let´s go over those three points again. First of all, MT is potent. It binds so strongly to the AR (androgen receptor) that it is often used in studies on other androgens to measure how strongly they bind. In other words, this stuff binds onto the AR receptor so strongly that it is pretty much the benchmark for that quality. If you´ve read my profile on Trenbolone Acetate (TA), you´ll note that I said TA is the most potent injectable weapon in our arsenal with regards to ability to bind to the Androgen receptor. That´s still true, because this particular compound is not in our arsenal, and it´s not injectable… it´s simply the oral version of TA (i.e. it is Trenbolone which has undergone modification to become orally active, via the addition of a 17-alph-methyl group). So why is it important that this stuff binds so tightly to the AR? Well, Androgen Receptors are found in both fat cells as well as muscle cells; they act on the AR in muscle cells to promote growth, and in the fat cells to affect fat burning. The stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose (fat)tissue. Unfortunately, that strong binding doesn´t also automatically mean that it will elicit the strongest possible anabolic response, nor that the weakest bind will elicit a weak anabolic response. Anadrol (oxymetholone) has the weakest bind to the AR possible (too low to be measured), and it produces a profound anabolic response, for example. Dianabol is simarly low, and produces a very good anabolic response. AR´s are found in both muscle tissue as well as adipose tissue. When a muscle´s AR is stimulated, it can induce hypertrophy. When an adipose tissue´s AR is stimulated, through various related mechanisms, fat is lost. This is a gross oversimplification. Whatever. All we need to know is that when you have a steroid that binds to the AR, it builds muscle and burns fat. And a steroid that binds very tightly to the AR will stimulate a lot of muscle synthesis and burn a lot of fat. A good example of this is Trenbolone. And since I mentioned Trenbolone, its worth further mentioning that MT is basically a 17aa (oral) version of (injectable) Trenbolone. AR binding and AR stimulation is not the only mechanism which stimulates anabolism, however. It is important to note that dbol has a very low AR binding ability and A50 has an AR binding ability which is too low to even measure! Both are very potent oral steroids, though. So while it´s important, AR binding/stimulation is not the end all & be all of anabolism, although it is an important part. Don´t be fooled by the anabolic/androgenic ratio of this (or any steroid), either. The anabolic/androgenic ratio of MT would suggest that it produces 120(+)x the anabolic and 60(+)x androgenic effect of Test-osterone (which has a score of 100 and 100 respectively). If one were able to get a bottle of this stuff, I believe it would be best used as part of a cutting cycle, stacked with some injectables (testo-steron, etc… ), but certainly no other orals. It´s just too toxic. Negma (the French company who brought Parabolan to the market, and then discontinued it) never pushed MT to gain approval as a commercially released item, since their original studies showed it to be highly toxic. Methyltrienolone is, of course, a 19Nor compound (as is Trenbolone)…Thus, it will effect your sexual drive and performance in a similar way to both Tren and Nandrolone, meaning that Temporary Impotence and/or a lack of libido is highly possible.(10). Another problem with MT is that it is a progestin, and binds shockingly well to the progesterone receptor also (PgR) . As we know, progestins amplify estrogenic effects of Aromatizing drugs. Although MT doesn´t aromatize, you will still need to worry about its ability to cause side-effects by amplifying the estrogenic issues caused by the other compounds you may be taking. How toxic is this stuff? Well, it was never commercially marketed for use in humans, and has been relegated to Steroid-Purgatory, to be used only in studies. I´d probably rate it on around the same level as taking very high doses of halotestin or methyltestosteron.
Posts Tagged ‘cycle’
Oral Tren
June 25th, 2010 
meetsteroids.com 
Posted in Steroid Profiles 
Tags: anabolic, anabolic steroids, cycle, oral, Oral tren, steroids, Tren 
5 Comments »Sarms S4
June 17th, 2010 meetsteroids.com 
SARMS S-4 and bridging. Is This The Perfect Drug To Use In-Between Steroid Cycles?
SARMS S-4 is the latest addition to the anabolic steroid using bodybuilder’s arsenal and it’s creating a storm of controversy. It may very well be most significant advancement in muscle development since the invention of Dianabol back in 1956. A bold statement for sure. But SARMS S-4 is truly an incredible compound with many applications, most significantly, as a viable anabolic enhancement to be used in-between steroid cycles which is also known as bridging (1).
SARMS S-4 is not a steroid. It is the veritable “next step” beyond steroids. It’s a Selective Androgen Receptor Modulator, which essentially means it targets your androgen receptors in a way where they’re most beneficial for building muscle while avoiding the nasty side effects that go along with traditional androgenic steroids (2).
Due to that elusive combination of good without the bad, SARMS S-4 has been hailed as the “Holy Grail of Muscle Growth.” It’s what all athletes have been waiting and wishing for. Think of it as pizza without calories, alcohol without the hangover and safe sex without condoms. Is that possible? Yes it is. But there are limitations. (Damn!) But rest assured, they’re minor. There is a catch – there always is. But in the case of SARMS S-4, the catch isn’t that bad.
For one thing, SARMS S-4 will not work like mega doses of steroids. You would not be able to take huge dosages in order to gain massive size on the order of a gram of testosterone. Its benefits work within a specific dosage range (3). In that regard, SARMS S-4 is unique. A good comparison would be to aspirin, which will always lower a temperature from a fever, but no lower than 98.6. However, MORE aspirin will not improve the condition. There’s that “sweet spot” where it works its magic with virtually no risk. SARMS S-4 is like that. In controlled dosages, it’s a non toxic, non testosterone suppressive compound that works like steroids, but without the side effects(4). But beyond a certain dosage, it does not work much better. It has a sort of “built in safety net.” Using 50ml a day is an effective dosage with 100mls a day being the cut-off point to avoid any negative side effects.
The potential and the possibilities are as compelling as they are enticing, but one area where SARMS S-4 is becoming increasingly popular is in the area of “bridging.”
A “bridge” is essentially a description for using any compound that will maintain the gains of your last steroid cycle until you decide to start your next cycle, however many months later. How to best bridge has been a controversial topic for some time. In the past, bodybuilders have attempted to sustain the effects of a steroid cycle by using a milder , less suppressive steroid (such as Primobolin) in-between cycles.
Another method of attempting a “bridge” was to use a short acting oral in the morning so that it would not be active past a four hour window. In this way, at least theoretically, you could recover over-night, resulting in your body managing to restore its natural hormonal balance. Unfortunately, neither game plan was especially successful for even a low dose of any steroid will cause suppression of your natural testosterone production and hinder recovery.
That’s where SARMS S-4 fits in… Remember, SARMS S-4 is not a steroid. It works on an entirely different principle – that of being “selective” to muscle. And at 50 mls a day it has’s been shown to have no suppressive effects. (Unless dosing exceeds several months)(5). This makes SARMS S-4 the perfect choice to be used in-between cycles. You won’t make massive gains while on but you’ll hold onto your gains and still be in an “enhanced” state without fear of suppression. Not a bad deal.
It would make far more sense to “bridge” using SARMS S-4 on its own, or with natural supplements in order for the body to maintain ultimate anabolism without suppression. As much as using a less suppressive steroid may seem to make sense, ANY steroid even in low dosages will suppress, delay recovery, and ultimately work against the process of recovering from a cycle. It will also minimize the results of the NEXT cycle since the receptors would not have had a chance to replenish(6) This is what makes SARMS S-4 superior for this purpose.
Another similar method that’s becoming popular is to use SARMS S-4 as a “mini-cycle” in-between steroid cycles. In other words, once you finish your course of steroids and do a proper PCT and settle into being “natural”, after a while you can use SARMS S-4 daily for a 4 week run. In this way you can bump up gains, increase muscle density, improve lifts and burn fat – all without deregulating androgen receptors or compromising the HPTA. (Hypothalamic Pituitary Testicular Axis)(7). Never before has this been possible.
A PCT following a SARMS S-4 cycle may not be necessary. Some OTC supplements may be all you need to get back to baseline. SARMS S-4 won’t aromatize so there’s no fear of developing gyno or other estrogen related conditions(8).
SARMS S-4 has many uses and having an anabolic/androgenic advantages while off cycle may be the most significant of all.
Posted in Legal Steroids Tags: bridge cycle, bridgeing, cycle, muscle, sarms, sarms s-4, steroids 30 Comments »
